I haven’t used the HUB75 matrices myself so I haven’t yet gone down the rabbit hole of mastering their rather unique pinout. I’m not sure what the best pinout would be for the Maker Feather S2 however I did want to let you know there are a couple of controllers out there with a HUB75 connector built in that feature a ESP32 co-processor.
Could you let me know what library your project was using to address the matrix and any resources you were drawing from? If we can find an existing project using a Feather S2 for this that may short-cut a lot of the trial and error we may encounter to get this running.
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