Hi Peter,
NVME drives require more power than normal SATA M.2 drives. The NVME drives will not work without a special drive enclosure and power source as the Pi 4’s USB ports cannot provide that high current. I think Argon one’s case and the added NVME enclosure provides power to the Pi via the power supply connected to the case and not directly to Pi as other cases.
Pi 4 has USB 3.0. So it is lesser than SATA 3. It will limit the speed. Posted my experience with a M.2 SSD here.
